PLGRKT Antibody, HRP conjugated

Code CSB-PA875713LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PLGRKT Polyclonal antibody
Uniprot No.
Target Names
PLGRKT
Alternative Names
PLGRKT; C9orf46; AD025; MDS030; Plasminogen receptor; KT; Plg-R(KT
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Plasminogen receptor (KT) protein (1-147AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metalloproteinase activation, such as of MMP2 and MMP9.
Gene References into Functions
  1. Plg-R(KT) was highly expressed in bovine adrenomedullary chromaffin cells, human pheochromocytoma tissue, PC12 pheochromocytoma cells, and murine hippocampus. PMID: 21795689
  2. Plg-R(KT) plays a key role in the plasminogen-dependent regulation of macrophage invasion, chemotactic migration, and recruitment in the inflammatory response. PMID: 21940822
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Tissue Specificity
Expressed in peripheral blood cells and monocytes. Expressed in adrenal medulla.
Database Links

HGNC: 23633

KEGG: hsa:55848

STRING: 9606.ENSP00000223864

UniGene: Hs.584242

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